Vaginal atrophy doesn’t have to affect every aspect of your patients’ lives

Prescribing and adverse event reporting information can be found at the end of this video.

About half of all postmenopausal women experience pain or discomfort due to vaginal atrophy, with their quality of life and relationships significantly affected.1,2

Vaginal atrophy can cause a multitude of signs and symptoms, including burning, vaginal dryness, in during sex, itching, and dysuria.3

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The videos cover a range of very useful, relevant and important topics including, the signs and symptoms of VA, how to make the diagnosis and the impact of vaginal atrophy on a patient’s quality of life.

How to give women support and treatment

Women may find it difficult to talk about the condition, as they may want their doctor to start the discussion.4

There are many reasons why women may feel they cannot discuss vaginal atrophy with their doctor, but can include thinking that there is no treatment, that the discussion is inappropriate, or finding the conversation embarrassing.5

Click here to watch our Challenges faced: Diagnosis video
Prescribing and adverse event reporting information can be found at the end of this video.

NICE guidance states that vaginal oestrogen should be offered to women to manage the bothersome symptoms of vaginal atrophy.6

Despite the clear treatment guidelines, 50% of women with genitourinary symptoms after the menopause have never been prescribed any medication for their symptoms.7

Using Blissel® to treat vaginal atrophy

Blissel® is an ultra low dose estriol vaginal gel containing 50 micrograms per dose (1 gram) of estriol, which is indicated for treating the symptoms of vaginal atrophy due to oestrogen deficiency in postmenopausal women.8,9

Blissel® is an effective treatment for postmenopausal women with VVA (Vulvovaginal Atrophy).8,9

Your patients may notice a rapid improvement in their symptoms from the initial days of treatment when you prescribe Blissel®.10

Please refer to safety information below.

Prescribing and adverse event reporting information can be found at the end of this video.

Prescribe Blissel® by brand for your patients to ensure the gel is not replaced when it is dispensed.

Prescribe Blissel® by brand for your patients. Blissel®is the first and only prescribable estriol containing gel for the treatment of vaginal atrophy8,9

Guidelines on the treatment of vaginal atrophy 

NICE guidelines provide clear direction that local therapy is preferable to systemic treatment for vaginal symptoms.6 Guidelines advocate to provide vaginal oestrogen to women to manage bothersome symptoms of vaginal atrophy.6

Despite clear guidelines, half of all women who experience genitourinary symptoms after the menopause have not received any treatment at all for their symptoms.7

Treating vaginal atrophy with Blissel®

Blissel® is an ultra low dose estriol vaginal gel containing 50 micrograms per dose (1 gram) of estriol, indicated for treating the symptoms of vaginal atrophy due to oestrogen deficiency in postmenopausal women.8,9

Blissel® is an effective treatment for postmenopausal women with VVA (Vulvovaginal Atrophy).8,9 Blissel® gives your patients a rapid improvement in their symptoms from the first days of treatment.10

Please refer to safety information below.

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How Blissel
Works

Efficacy

Dosing

Ultra low dose estriol vaginal gel8,9

Prescribing and Adverse event reporting information for Blissel can be found here.

 Adverse events should be reported. Reporting forms and information can be found at yellowcard.mhra.gov.uk or search for MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to Consilient Health (UK) Ltd, No. 1 Church Road, Richmond upon Thames, Surrey TW9 2QE UK or drugsafety@consilienthealth.com 

1. Nappi RE, Palacios S. Climacteric. 2014;17:3–9. 2. Moral E, et al. Menopause. 2018;25(12):1418-23.
3. Palma F, et al. Maturitas. 2018;108:18–23. 4. Krychman M, et al. J Sex Med 2017;14:425-433.
5. Kagan R, et al. Drugs Aging. 2019;36:897–908. 6. NICE. Menopause: diagnosis and management (NG23). Available from: https://
www.nice.org.uk/guidance/ng23/chapter/recommendations. Accessed December 2023.
7. NAMS position statement. Menopause. 2020;27(9):976-92. 8. Blissel 50 micrograms/g vaginal gel. Summary of product characteristics.
9. Cano A, et al. Menopause. 2012;19(10):1130-9. 10. Lázaro-Carrasco de la Fuente J, et al. J Menopausal Med. 2022;28(2):60-69.

Date of preparation: February 2026 | UK-BLS-626(2)

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  • For the treatment of postmenopausal vaginal atrophy symptoms, local estrogen therapy should only be initiated for symptoms that adversely affect quality of life.
  • Blissel 50 micrograms/g vaginal gel must not be combined with estrogen preparations for systemic treatment, as there are no studies of safety and risks with estrogen concentrations attained in combination treatment.
  • Intravaginal applicator may cause minor local trauma, especially in women with serious vaginal atrophy.
  • Before estriol treatment is initiated or reinstituted, a complete personal and family medical history should be taken. Physical (including pelvic and breast) examination should be guided by this and by the contraindications and warnings for use.

Please refer to the Summary of Product Characteristics before prescribing.1

1. Blissel 50 micrograms/g vaginal gel. Summary of product characteristics.

Common (1/100 to <1/10) and (1/1000 to <1/100) undesirable effects1


Date of preparation: April 2026 Item code: UK-BLS-671(1)