Help support women on their vaginal atrophy journey

Prescribing and Adverse event reporting information for Blissel can be found here.

Women may want their healthcare professional to lead conversations about VA, even though understanding the condition is important to them.1

You can help stop the progressive changes due to vaginal atrophy (VA) with earlier diagnosis, and support women’s quality of life.2-4

Please refer to safety information below.

Prescribing and adverse event reporting information can be found at the end of this video.

The diagnosis of vaginal atrophy is not always straightforward

Complicating the diagnosis of vaginal atrophy is the fact that it can present in various ways, including vaginal dryness, dysuria, itching, burning, and pain during sex.5

Women may be reluctant to discuss the symptoms of vaginal atrophy, due to feelings such as discomfort, concern that the topic isn’t appropriate to raise, or the belief that nothing can be done.6

Prescribing and adverse event reporting information can be found at the end of this video.

Prescribing and Adverse event reporting information for Blissel can be found here.

Women may want their healthcare professional to lead conversations about VA, even though understanding the condition is important to them.1

You can help stop the progressive changes due to vaginal atrophy (VA) with earlier diagnosis, and support women’s quality of life.2-4

Prescribing and adverse event reporting information can be found at the end of this video.

Prescribing and adverse event reporting information can be found at the end of this video.

The diagnosis of vaginal atrophy is not always straightforward

Complicating the diagnosis of vaginal atrophy is the fact that it can present in various ways, including vaginal dryness, dysuria, itching, burning, and pain during sex.5

Women may be reluctant to discuss the symptoms of vaginal atrophy, due to feelings such as discomfort, concern that the topic isn’t appropriate to raise, or the belief that nothing can be done.6

My Blissel® Time to talk
Video Library

A library of discussions led by national experts Dr Anne Connolly, Dr Diana Mansour and Nurse Specialist Consultant Nikki Noble.
The videos cover a range of very useful, relevant and important topics including, the signs and symptoms of VA, how to make the diagnosis and the impact of vaginal atrophy on a patients quality of life.

Prescribe Blissel® by brand for your patients.

Blissel® is the first and only prescribable estriol containing gel for the treatment of vaginal atrophy7,8

Please refer to safety information below.

Please refer to the Summary of Product Characteristics before prescribing.8

Patients have difficulty discussing their condition

For reasons that are understandable, women may hesitate when discussing vaginal symptoms.6

Whilst there can be many motivations, they can commonly include embarrassment, feeling the discussion is inappropriate, or that nothing can be done.6

Blissel®treats the bothersome symptoms of vaginal atrophy

Blissel® is an ultra low dose estriol vaginal gel containing 50 micrograms per dose (1 gram) of estriol, indicated for treating the symptoms of vaginal atrophy due to oestrogen deficiency in postmenopausal women.7,8


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How Blissel
Works

Efficacy

Dosing

Ultra low dose estriol vaginal gel7,8

Prescribing and Adverse event reporting information for Blissel can be found here.

 Adverse events should be reported. Reporting forms and information can be found at yellowcard.mhra.gov.uk or search for MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to Consilient Health (UK) Ltd, No. 1 Church Road, Richmond upon Thames, Surrey TW9 2QE UK or drugsafety@consilienthealth.com 

  1. Krychman M, et al. J Sex Med 2017;14:425-433.
  2. Moral E, et al. Menopause. 2018;25(12):1418-23.
  3. Cagnacci A, et al. Climacteric. 2019;22(1):85-89.
  4. NAMS position statement. Menopause. 2020;27(9):976-92.
  5. Palma F, et al. Maturitas. 2018;108:18–23.
  6. Kagan R, et al. Drugs Aging. 2019;36:897–908.
  7. Cano A, et al. Menopause. 2012;19(10):1130-9.
  8. Blissel 50 micrograms/g vaginal gel. Summary of product characteristics.

Date of preparation: February 2026 | UK-BLS-615(2)

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  • For the treatment of postmenopausal vaginal atrophy symptoms, local estrogen therapy should only be initiated for symptoms that adversely affect quality of life.
  • Blissel 50 micrograms/g vaginal gel must not be combined with estrogen preparations for systemic treatment, as there are no studies of safety and risks with estrogen concentrations attained in combination treatment.
  • Intravaginal applicator may cause minor local trauma, especially in women with serious vaginal atrophy.
  • Before estriol treatment is initiated or reinstituted, a complete personal and family medical history should be taken. Physical (including pelvic and breast) examination should be guided by this and by the contraindications and warnings for use.

Please refer to the Summary of Product Characteristics before prescribing.1

1. Blissel 50 micrograms/g vaginal gel. Summary of product characteristics.

Common (1/100 to <1/10) and (1/1000 to <1/100) undesirable effects1


Date of preparation: April 2026 Item code: UK-BLS-671(1)